Constitutive parameter identifiability and the design of experiments for applications in breast biomechanics (Video) Event as iCalendar


17 May 2016

4 - 5pm

Venue: Ground Floor Seminar Room (G10)

Location: 70 Symonds Street, Auckland Central

Prasad Babarenda Gamage

A Bioengineering exit seminar by Thiranja Prasad Babarenda Gamage, Auckland Bioengineering Institute


My PhD involved the development of biomechanical models of the breast to help clinicians locate tumours during breast cancer treatment procedures. Successful application of these models depends on their ability to make reliable predictions of tissue motion. Robust identification of the constitutive parameters, describing the mechanical behaviour of an individual’s breast tissues, is therefore required.

The first part of my thesis involved validating the modelling of soft layered bodies by performing experiments on synthetic materials. These studies provided a platform for investigating issues related to identifying constitutive parameters, and for developing methods for improving parameter identifiably. An individual-specific breast biomechanical model was then developed and its constitutive parameters identified from breast repositioning studies performed under MR imaging. Lastly, a model based design of experiments procedure was developed for determining optimal experimental protocols for identifying breast constitutive parameters using only measurements from the surface of the skin under gravity loading.

About the Speaker

Thiranja Prasad Babarenda Gamage received a Bachelor of Biomedical Engineering with Honours from the University of Auckland in 2008, and subsequently began a PhD at the Auckland Bioengineering Institute.