Extending Subject-Specific Biomechanical Models to Populations (Video) Event as iCalendar

(Seminars)

21 February 2017

4 - 5pm

Venue: Ground Floor Seminar Room (G10)

Location: 70 Symonds St, Auckland Central

An ABI seminar by Professor Peter J Laz, Center for Orthopaedic Biomechanics, Mechanical and Materials Engineering, University of Denver.

Abstract

To accurately capture a subject’s biomechanics, models typically require subject-level specificity.  Inherently, there are subject-to-subject differences in anatomy, tissue properties and motions/loading.  Often this variability can be a confounding factor in clinical research.  Detailed subject-specific models have shown the ability to successfully predict joint mechanics, but questions remain of how to extend results of models and experiments to the population at large, with broad goals of diagnosing pathology, informing implant design and overall, improving patient outcomes. This seminar will describe current efforts in our Center to address some of these challenges and will include predictions of subject-specific fracture patterns, development of statistical models to describe the anatomy of whole joints with applications to fluoroscopy and sparse data predictions, creation of an open source probabilistic toolbox for muscle force prediction and recent work on population-based analyses.