Auckland Bioengineering Institute


Marc Jacobs

jacobs-marc

Alumnus profile

Marc Jacobs' research used imaging modalities to acquire data on tissue structure and function, which inform biophysical, integrative modelling of tissues and organs.

Marc studied the skin, blood vessel and eye systems, and the gap junction channels and other cellular components. The imaging approaches taken to these systems have included multiphoton and confocal microscopy, MRI and microCT.

The long-term aim of Marc's imaging and modelling research was to expand the field of 'Integrative Biology' to include empirically-informed, continuum modelling at the cell and tissue scales. This entailed using and extending techniques from multiscale computational modelling, systems biology, physiology and molecular cell biology. These aims and technical approaches helped integrate our understanding from genes to whole cell function, with benefits in the areas of biomedicine and biotechnology.