Alison Schroeder

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ME student

Contact details

Uniservices House
70 Symonds St
Auckland

Phone: 09 9233010; ext 83010

Biography

Alison graduated from NJIT in May 2016 with a B.S. in biomedical engineering and a minor in business.  After graduation Alison worked for the global pharmaceutical company Merck (known as MSD outside of the US) until starting here at ABI in early 2017.  Alison's research project is funded in part by the Whitaker Fellowship offered through Institute of International Education.

Thesis

Modelling cardiac excitation-contraction mechanics based on trabecula myometry

The ABI’s cardiac myometer has been used to gather a rich variety of physiological recordings from intact trabeculae (tissue strips isolated from the inner ventricular wall) undergoing fixed-length (isometric) contractions. The data show that contractions involved heterogeneous distributions of muscle cross-sectional areas and sarcomere lengths along the length of the samples.  Even though the lengths of the muscles were held constant, the ‘thicker’ regions of the trabeculae tended to shorten, while the ‘thinner’ regions tended to stretch.  The goal of this project is to develop a 3D computational model of cardiac trabeculae mechanics to understand the mechanisms that underpin this phenomenon.

Supervisors

Dr Kenneth Tran

Associate Professor Denis Loiselle

Professor Martyn Nash

Dr David Nickerson