Auckland Bioengineering Institute


The 'garden hose' effect

bioinst-garden-hose

The ABI Bioinstrumentation Lab is investigating the influence of perfusion on tissue mechanics, with the goal of better understanding how organs behave mechanically and investigating potential new engineering materials. Many biological tissues exhibit increased stiffness when perfusion pressure is increased, known as the “garden-hose” effect.

Experiments are being carried out on simplified gel models of perfused tissue in order to quantitatively determine the influence of perfusion pressure on the mechanics of a material. Results from these experiments are directing the development of computational models of perfused tissue, which are validated experimentally with mechanical testing of skeletal muscle.

Project members


Contributors

Adam Reeve

Adam Reeve
2010-2014, PhD student
Mechanics of vascularised tissue

Funding partner


  • The University of Auckland Doctoral Scholarship