Miss Hui Ren

MSc

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Doctoral Candidate - Doctor of Philosophy

Biography

Hui attained a Master of Science in Pathophysiology from Beijing University, China,  before joining the Auckland Bioengineering Institute as a PhD student in 2012.
 

Research | Current

Ion and water transport in human alveolar epithelial cells

The thickness and composition of the surface liquid lining the human lungs are maintained by a balance between epithelial secretion and absorption of ions and water. An understanding of epithelial transport pathways and the factors that regulate them will provide insight into the development of conditions such as lung edema and guide the development of treatment modalities. A cell culture model of the alveolar epithelium was developed using the human alveolar epithelial cell lines H441 and A549. The paracellular and transcellular transport properties under this model were characterised. It will be useful for investigating the components of epithelial transport pathways and interpreting molecular mechanisms involved in transport related diseases.

Supervisors

Selected publications and creative works (Research Outputs)

  • Ren, H., Birch, N. P., & Suresh, V. (2016). Barrier function and ion transport in an oleic acid-induced model of lung injury. Proceedings of the AuPS, 47, 92P-92P. Adelaide, Australia: Australian Physiological Society (AuPS). Related URL.
    URL: http://hdl.handle.net/2292/31295
    Other University of Auckland co-authors: Vinod Suresh, Nigel Birch
  • Huang, X., He, D., Ming, J., He, Y., Zhou, C., Ren, H., ... Ji, L. (2016). High-density lipoprotein of patients with breast cancer complicated with type 2 diabetes mellitus promotes cancer cells adhesion to vascular endothelium via ICAM-1 and VCAM-1 upregulation. Breast cancer research and treatment, 155 (3), 441-455. 10.1007/s10549-016-3696-0
  • Ren, H. (2016). Transport properties of cell culture models of the alveolar epithelium The University of Auckland. ResearchSpace@Auckland.
  • Ren, H., Birch, N. P., & Suresh, V. (2016). An Optimised Human Cell Culture Model for Alveolar Epithelial Transport. PloS one, 11 (10)10.1371/journal.pone.0165225
    URL: http://hdl.handle.net/2292/31285
    Other University of Auckland co-authors: Vinod Suresh, Nigel Birch
  • He, D., Pan, B., Ren, H., & Zheng, L. (2014). Effects of diabetic HDL on endothelial cell function. Cardiovascular & hematological disorders drug targets, 14 (2), 137-141. 10.2174/1871529x14666140505124415
  • Pan, B., Yu, B., Ren, H., Willard, B., Pan, L., Zu, L., ... Niu, C. (2013). High-density lipoprotein nitration and chlorination catalyzed by myeloperoxidase impair its effect of promoting endothelial repair. Free radical biology & medicine, 60, 272-281. 10.1016/j.freeradbiomed.2013.02.004
  • Pan, B., Ren, H., Ma, Y., Liu, D., Yu, B., Ji, L., ... Lv, X. (2012). High-density lipoprotein of patients with type 2 diabetes mellitus elevates the capability of promoting migration and invasion of breast cancer cells. International journal of cancer, 131 (1), 70-82. 10.1002/ijc.26341
  • Pan, B., Ren, H., He, Y., Lv, X., Ma, Y., Li, J., ... Niu, C. (2012). HDL of patients with type 2 diabetes mellitus elevates the capability of promoting breast cancer metastasis. Clinical cancer research : an official journal of the American Association for Cancer Research, 18 (5), 1246-1256. 10.1158/1078-0432.ccr-11-0817

Identifiers

Contact details

Primary location

THOMAS BUILDING - Bldg 110
Level 2 , Room 228L
3 SYMONDS ST
AUCKLAND 1010
New Zealand

Secondary location

UNISERVICES HOUSE - Bldg 439
Level 7 , Room 721
70 SYMONDS ST
AUCKLAND 1010
New Zealand

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