Dr James William McKeage

Ph.D (Bioengineering), BE (Hons)

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Research Fellow

Biography

James McKeage is a Research Fellow with the Bioinstrumentation Lab at the Auckland Bioengineering Institute. His work focuses on needle-free jet injection technology, a technique where fluid drugs are delivered as a fine, high-speed jet.  James’ work seeks to understand how this technique can be applied to improve patient outcomes, and the application of jet injection to new drug delivery challenges.

After completing his undergraduate degree in Biomedical Engineering at the University of Auckland, James joined the Bioinstrumentation lab as a PhD student. During his PhD James investigated the effects of injection volume on needle-free jet injection and investigated tools to increase the scope of this technology. In 2018 James completed his PhD and started as a Research Fellow in the Bioinstrumentation Lab.

Research | Current

James’ work is primarily in the field of needle-free jet injection, a drug delivery technique that forms the drug into a high speed jet capable of breaking the skin without a needle. As well as developing the underlying technology James is involved with the application of this technique to multiple drug delivery challenges. Recently his work has focussed on the delivery of local anaesthetic, and the application of jet injection technology to the treatment of diabetes.

 

Research groups/projects

Selected publications and creative works (Research Outputs)

As of 29 October 2020 there will be no automatic updating of 'selected publications and creative works' from Research Outputs. Please continue to keep your Research Outputs profile up to date.
  • Xu, J., McKeage, J. W., Ruddy, B. P., Nielsen, P. M. F., & Taberner, A. J. (2020). Blood Collection from the Porcine Ear Using a Jet Injector. Proceedings of the Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS. 10.1109/EMBC44109.2020.9175421
    Other University of Auckland co-authors: Andrew Taberner, Poul Nielsen, Bryan Ruddy
  • Madadkhahsalmassi, B., McKeage, J., Ruddy, B., & Taberner, A. (2020). Blood dilution measurement by a dual laser fluorimeter. I2MTC 2020 - International Instrumentation and Measurement Technology Conference, Proceedings. 10.1109/I2MTC43012.2020.9128472
    Other University of Auckland co-authors: Bryan Ruddy, Andrew Taberner
  • Williams, R. M. J., McKeage, J. W., Ruddy, B. P., Nielsen, P. M. F., & Taberner, A. J. (2019). Viscous Heating Assists Jet Formation During Needle-Free Jet Injection of Viscous Drugs. IEEE transactions on bio-medical engineering, 66 (12), 3472-3479. 10.1109/tbme.2019.2906356
    Other University of Auckland co-authors: Bryan Ruddy, Andrew Taberner, Poul Nielsen
  • McKeage, J. W., Abeysekera, N., Ruddy, B. P., Nielsen, P. M. F., & Taberner, A. J. (2019). Laterally Dispersing Nozzles for Needle-assisted Jet Injection. Proceedings 2019 41st Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC), 1686-1689. Berlin, Germany: IEEE. 10.1109/EMBC.2019.8856319
    Other University of Auckland co-authors: Bryan Ruddy, Poul Nielsen, Andrew Taberner
  • Ruddy, B. P., Bullen, C., Chu, J. T. W., Jeong, S. H., Madadkhahsalmassi, B., McKeage, J. W., ... Taberner, A. J. (2019). Subcutaneous nicotine delivery via needle-free jet injection: A porcine model. Journal of controlled release : official journal of the Controlled Release Society, 306, 83-88. 10.1016/j.jconrel.2019.05.040
    Other University of Auckland co-authors: Bryan Ruddy, Chris Bullen, Joanna Chu, Soo Hee Jeong, Darren Svirskis, Malcolm Tingle, Andrew Taberner
  • McKeage, J. W., Ruddy, B. P., Nielsen, P. M. F., & Taberner, A. J. (2018). Power-efficient controlled jet injection using a compound ampoule. Journal of Controlled Release, 291, 127-134. 10.1016/j.jconrel.2018.10.025
    Other University of Auckland co-authors: Bryan Ruddy, Andrew Taberner, Poul Nielsen
  • McKeage, J. W., Ruddy, B. P., Nielsen, P. M. F., & Taberner, A. J. (2018). The effect of jet speed on large volume jet injection. Journal of controlled release : official journal of the Controlled Release Society, 280, 51-57. 10.1016/j.jconrel.2018.04.054
    Other University of Auckland co-authors: Bryan Ruddy, Poul Nielsen, Andrew Taberner
  • Mckeage, J. W. (2018). Large Volume Jet Injection The University of Auckland. ResearchSpace@Auckland.

Identifiers

Contact details

Primary office location

AUCKLAND BIOENGINEERING HOUSE - Bldg 439
Level G, Room G12
70 SYMONDS ST
GRAFTON
AUCKLAND 1010
New Zealand

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