Mr Kieran An Brennan

BE(Hons)

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Doctoral Candidate - Doctor of Philosophy

Biography

Kieran has a Bachelor of Engineering (Honours) in Engineering Science from the University of Auckland. He commenced doctoral study at the Auckland Bioengineering Institute in 2015.
 

Research | Current

Thesis

Real-time Fluid Penetration Imaging for Needle-Free Jet-Injection

Needle-free jet injection is a method of drug delivery whereby a liquid drug is pressurised and accelerated to form a narrow jet that can penetrate the skin and the underlying tissue. A difficulty with needle-free injection is dynamically determining the depth of fluid penetration. This is an important issue to address in order to safely administer a drug to the appropriate tissue layer for desirable absorption.

My PhD research is concerned with developing a sensing system that can measure the penetration depth of the injection in real-time. This would allow feedback to the jet injection control system to regulate injection speed, enabling drug delivery at the desired depth. 


Supervisors

 

Research groups/projects

Selected publications and creative works (Research Outputs)

  • Brennan, K. A., Kulasingham, D. A. N., Nielsen, P. M. F., Taberner, A. J., & Ruddy, B. P. (2019). High-speed light source depth estimation using spatially-resolved diffuse imaging. JOURNAL OF OPTICS, 21 (1)10.1088/2040-8986/aaf4db
    Other University of Auckland co-authors: Bryan Ruddy, Poul Nielsen, Andrew Taberner
  • Brennan, K. A., Ruddy, B. P., Nielsen, P. M. P., & Taberner, A. J. (2018). High speed, spatially-resolved diffuse imaging for jet injection depth estimation. Paper presented at Conference on Dynamics and Fluctuations in Biomedical Photonics XV, San Francisco, CA. 28 January - 29 January 2018. DYNAMICS AND FLUCTUATIONS IN BIOMEDICAL PHOTONICS XV. (pp. 7). 10.1117/12.2288874
    Other University of Auckland co-authors: Poul Nielsen, Bryan Ruddy, Andrew Taberner
  • McKeage, J., Brennan, K., Park, G., Hogan, N., Hunter, I., Ruddy, B., ... Taberner, A. (2017). High-speed X-ray analysis of liquid delivery during jet injection. Engineering in Medicine and Biology Society (EMBC), 2017 39th Annual International Conference of the IEEE, 296-299. Seogwipo, South Korea. 10.1109/EMBC.2017.8036821
    URL: http://hdl.handle.net/2292/44448
    Other University of Auckland co-authors: Bryan Ruddy, James McKeage, Poul Nielsen, Andrew Taberner
  • Brennan, K. A., Ruddy, B. P., Nielsen, P. M. F., & Taberner, A. J. (2016). Light source depth estimation in porcine skin using spatially resolved diffuse imaging. 2016 IEEE 38th Annual International Conference of the Engineering in Medicine and Biology Society (EMBC), 5917-5920. Orlando, FL. 10.1109/EMBC.2016.7592075
    URL: http://hdl.handle.net/2292/32735
    Other University of Auckland co-authors: Bryan Ruddy, Poul Nielsen, Andrew Taberner

Identifiers

Contact details

Primary office location

UNISERVICES HOUSE - Bldg 439
70 SYMONDS ST
AUCKLAND 1010
New Zealand

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