Mr Kieran Brennan
Kieran has a Bachelor of Engineering (Honours) in Engineering Science from the University of Auckland. He commenced doctoral study at the Auckland Bioengineering Institute in 2015.
Research | Current
Real-time Fluid Penetration Imaging for Needle-Free Jet-Injection
Needle-free jet injection is a method of drug delivery whereby a liquid drug is pressurised and accelerated to form a narrow jet that can penetrate the skin and the underlying tissue. A difficulty with needle-free injection is dynamically determining the depth of fluid penetration. This is an important issue to address in order to safely administer a drug to the appropriate tissue layer for desirable absorption.
My PhD research is concerned with developing a sensing system that can measure the penetration depth of the injection in real-time. This would allow feedback to the jet injection control system to regulate injection speed, enabling drug delivery at the desired depth.
Selected publications and creative works (Research Outputs)
- Brennan, K. A., Ruddy, B. P., Nielsen, P. M. F., & Taberner, A. J. (2016). Light source depth estimation in porcine skin using spatially resolved diffuse imaging. 2016 IEEE 38th Annual International Conference of the Engineering in Medicine and Biology Society (EMBC), 5917-5920. Orlando, FL. 10.1109/EMBC.2016.7592075
Other University of Auckland co-authors: Bryan Ruddy, Poul Nielsen, Andrew Taberner