Professor Poul Michael Fonss Nielsen
BSc BE PhD
Poul has a Bachelor of Science in Maths and Physics, and a Bachelor of Engineering and Phd in Engineering Science, from the University of Auckland.
Poul is affiliated with several groups within the University:
Research | Current
Poul's research focuses on using novel instrumentation, detailed computational models, and quantitative descriptions of physical processes to gain a better understanding of human physiology. Many of his projects couple mathematical modelling with innovative instrumentation to improve our ability to understand and interpret measurements of complex biological systems, subject to the constraints of well-understood physical conservation and balance laws.
Poul's research projects include:
- Physiome: an integrated multi-centric program to design, develop, implement, test and document, archive and disseminate quantitative information and integrative models of the functional behaviour of organelles, cells, tissues, organs, and organisms;
- CellML: an open standard to store and exchange computer-based mathematical models;
- FieldML: a declarative language for representing the dynamic geometry and solution fields of computational models;
- Breast mechanics: computational biomechanical models to improve the detection of breast cancer using information obtained from a variety of imaging modalities;
- Muscle microcalorimetry: to identify the dynamic stiffness of isolated rat trabeculae while simultaneously recording muscle heat production;
- Soft tissue mechanics: coupling large deformation theory, structurally-based constitutive relations, and nonlinear identification techniques to understand the mechanics of soft tissues;
- Pelvic floor mechanics: modelling the second stage of labour and pelvic floor prolapse;
- Modelling shaken baby syndrome: gaining an understanding of the relationships between shaking insults and soft tissue injury in infants;
- Bioinstrumentation and medical devices: development of novel instrumentation for measuring biophysical properties of living tissue (microrobotics, stereoscopy, optical coherence tomography, spectral imaging, interferometry).
- Thiranja Prasad Babarenda Gamage, Modelling and identifying the mechanical properties of skin and underlying tissues
- Amir Haji Rassouliha, Hardware acceleration of cross-correlation-based identification of surface geometry of deformable bodies
- Matthew Parker, Model-based identification of the mechanical properties of living skin
- Nikini Puhulwelle Gamage, Model-based prediction of brain injury associated with shaken baby syndrome
- Adam Reeve,The mechanics of vascularised tissue
- Samuel Richardson, Development of an optical coherence tomography based skin cancer diagnostic tool
- Oliver Thompson, Interpretation and Medical Application of Laser Biospeckle
- 2011 - 2013: James Cook Research Fellowship, Royal Society of New Zealand.
- 2011 - present: Liggins Institute Honorary Professor.
- 2010: OCCAM Visiting Fellow, University of Oxford.
Selected publications and creative works (Research Outputs)
- McKeage, J. W., Ruddy, B. P., Nielsen, P. M. F., & Taberner, A. J. (2018). The effect of jet speed on large volume jet injection. Journal of controlled release : official journal of the Controlled Release Society, 280, 51-57. 10.1016/j.jconrel.2018.04.054
Other University of Auckland co-authors: Bryan Ruddy, James Mckeage, Andrew Taberner
- Brennan, K. A., Ruddy, B. P., Nielsen, P. M. F., & Taberner, A. J. (2018). High speed spatially resolved diffuse imaging for jet injection depth estimation. Progress in Biomedical Optics and Imaging - Proceedings of SPIE. 10.1117/12.2288874
Other University of Auckland co-authors: Bryan Ruddy, Andrew Taberner
- Dixon, A. W., Taberner, A. J., Nash, M. P., & Nielsen, P. M. F. (2018). Extended depth measurement for a Stokes sample imaging polarimeter. Progress in Biomedical Optics and Imaging - Proceedings of SPIE. 10.1117/12.2289311
Other University of Auckland co-authors: Alex Dixon, Andrew Taberner, Martyn Nash
- Taberner, A. J., Zgierski-Johnston, C. M., Pham, T., Han, J.-C., Uddin, R., Loiselle, D. S., ... Nielsen, P. M. F. (2018). A Flowthrough Infusion Calorimeter for Measuring Muscle Energetics: Design and Performance. IEEE Transactions on Instrumentation and Measurement, 1-10. 10.1109/TIM.2018.2800838
Other University of Auckland co-authors: Denis Loiselle, Andrew Taberner, June-Chiew Han, Bryan Ruddy, Toan Pham
- Schneider, M. T., Zhang, J., Crisco, J. J., Weiss, A.-P. C., Ladd, A. L., Mithraratne, K., ... Besier, T. (2017). Trapeziometacarpal joint contact varies between men and women during three isometric functional tasks. Medical Engineering and Physics, 50, 43-49. 10.1016/j.medengphy.2017.09.002
Other University of Auckland co-authors: Kumar Mithraratne, Thor Besier, Marco Schneider, Ju Zhang
- Lintern, T. O., Nash, M. P., Kelly, P., Bloomfield, F. H., Taberner, A. J., & Nielsen, P. M. F. (2017). Probabilistic description of infant head kinematics in abusive head trauma. Computer methods in biomechanics and biomedical engineering, 20 (16), 1633-1642. 10.1080/10255842.2017.1403593
Other University of Auckland co-authors: Martyn Nash, Frank Bloomfield, Patrick Kelly
- Goh, C. M., Nielsen, P. M. F., & Nash, M. P. (2017). A stabilised mixed meshfree method for incompressible media: Application to linear elasticity and stokes flow. Computer Methods in Applied Mechanics and Engineering10.1016/j.cma.2017.10.002
Other University of Auckland co-authors: Martyn Nash
- Kruger, J. A., Budgett, S. C., Wong, V., Nielsen, P. M. F., Nash, M. P., Smalldridge, J., ... Taberner, A. J. (2017). Characterizing levator-ani muscle stiffness pre- and post-childbirth in European and Polynesian women in New Zealand: A pilot study. Acta Obstetricia et Gynecologica Scandinavica, 96 (10), 1234-1242. 10.1111/aogs.13186
Other University of Auckland co-authors: Jennifer Kruger, Stephanie Budgett, Martyn Nash, Jackie Smalldridge, Andrew Taberner