Professor Poul Michael Fonss Nielsen
BSc BE PhD
Poul has a Bachelor of Science in Maths and Physics, and a Bachelor of Engineering and Phd in Engineering Science, from the University of Auckland.
Poul is affiliated with several groups within the University:
Research | Current
Poul's research focuses on using novel instrumentation, detailed computational models, and quantitative descriptions of physical processes to gain a better understanding of human physiology. Many of his projects couple mathematical modelling with innovative instrumentation to improve our ability to understand and interpret measurements of complex biological systems, subject to the constraints of well-understood physical conservation and balance laws.
Poul's research projects include:
- Physiome: an integrated multi-centric program to design, develop, implement, test and document, archive and disseminate quantitative information and integrative models of the functional behaviour of organelles, cells, tissues, organs, and organisms;
- CellML: an open standard to store and exchange computer-based mathematical models;
- FieldML: a declarative language for representing the dynamic geometry and solution fields of computational models;
- Breast mechanics: computational biomechanical models to improve the detection of breast cancer using information obtained from a variety of imaging modalities;
- Muscle microcalorimetry: to identify the dynamic stiffness of isolated rat trabeculae while simultaneously recording muscle heat production;
- Soft tissue mechanics: coupling large deformation theory, structurally-based constitutive relations, and nonlinear identification techniques to understand the mechanics of soft tissues;
- Pelvic floor mechanics: modelling the second stage of labour and pelvic floor prolapse;
- Modelling shaken baby syndrome: gaining an understanding of the relationships between shaking insults and soft tissue injury in infants;
- Bioinstrumentation and medical devices: development of novel instrumentation for measuring biophysical properties of living tissue (microrobotics, stereoscopy, optical coherence tomography, spectral imaging, interferometry).
- Thiranja Prasad Babarenda Gamage, Modelling and identifying the mechanical properties of skin and underlying tissues
- Amir Haji Rassouliha, Hardware acceleration of cross-correlation-based identification of surface geometry of deformable bodies
- Matthew Parker, Model-based identification of the mechanical properties of living skin
- Nikini Puhulwelle Gamage, Model-based prediction of brain injury associated with shaken baby syndrome
- Adam Reeve,The mechanics of vascularised tissue
- Samuel Richardson, Development of an optical coherence tomography based skin cancer diagnostic tool
- Oliver Thompson, Interpretation and Medical Application of Laser Biospeckle
- 2011 - 2013: James Cook Research Fellowship, Royal Society of New Zealand.
- 2011 - present: Liggins Institute Honorary Professor.
- 2010: OCCAM Visiting Fellow, University of Oxford.
Selected publications and creative works (Research Outputs)
- Cheuk, M. L., Anderson, A. J., Han, J.-C., Lippok, N., Vanholsbeeck, F., Ruddy, B. P., ... Taberner, A. J. (2017). Four-Dimensional Imaging of Cardiac Trabeculae Contracting In Vitro Using Gated OCT. IEEE transactions on bio-medical engineering, 64 (1), 218-224. 10.1109/tbme.2016.2553154
Other University of Auckland co-authors: Andrew Taberner, June-Chiew Han, Frederique Vanholsbeeck, Bryan Ruddy, Denis Loiselle
- Cooling, M. T., Nickerson, D., Nielsen, P., & Hunter, P. (2016). Modular Modelling with Physiome Standards. The Journal of Physiology, 594 (23), 6817-6831. 10.1113/JP272633
Other University of Auckland co-authors: Mike Cooling, Peter Hunter, David Nickerson
- Parker, M. D., Jones, L. A., Hunter, I. W., Taberner, A. J., Nash, M. P., & Nielsen, P. M. F. (2016). Multidirectional In Vivo Characterization of Skin Using Wiener Nonlinear Stochastic System Identification Techniques. Journal of Biomechanical Engineering, 139 (1), 011004-011004. 10.1115/1.4034993
Other University of Auckland co-authors: Andrew Taberner, Martyn Nash
- Yan, X., Kruger, J. A., Li, X., Nielsen, P. M. F., & Nash, M. P. (2016). Modeling the second stage of labor. Wiley Interdisciplinary Reviews: Systems Biology and Medicine, 8 (6), 506-516. 10.1002/wsbm.1351
Other University of Auckland co-authors: Jennifer Kruger, Martyn Nash
- Mckeage, J. W., Ruddy, B. P., Nielsen, P. M. F., & Taberner, A. J. (2016). A device for controlled jet injection of large volumes of liquid.. United States. Conf Proc IEEE Eng Med Biol Soc. 10.1109/EMBC.2016.7590762
Other University of Auckland co-authors: Bryan Ruddy, James Mckeage, Andrew Taberner
- Brennan, K. A., Ruddy, B. P., Nielsen, P. M. F., & Taberner, A. J. (2016). Light source depth estimation in porcine skin using spatially resolved diffuse imaging.. Conference proceedings : ... Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual Conference. 10.1109/embc.2016.7592075
Other University of Auckland co-authors: Bryan Ruddy, Kieran Brennan, Andrew Taberner
- (2016). Abstracts. Neurourology and Urodynamics. 10.1002/nau.23074
Other University of Auckland co-authors: Jennifer Kruger, Jackie Smalldridge
- Tian, T., Budgett, S., Stinear, J., Smalldridge, J., Hayward, L., Nielsen, P., & Kruger, J. (2016). IS IT WHAT YOU DO OR THE WAY YOU DO IT?. Paper presented at Annual Meeting of the International-Continence-Society (ICS), Tokyo, JAPAN. 13 September - 16 September 2016. NEUROUROLOGY AND URODYNAMICS. (pp. 3).
Other University of Auckland co-authors: Stephanie Budgett, James Stinear, Jennifer Kruger, Jackie Smalldridge