Dr Thiranja Prasad Babarenda Gamage

BE(Hons) PhD Auck.

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Research Fellow

Biography

Thiranja Prasad Babarenda Gamage received a Bachelor of Biomedical Engineering with Honours from the Department of Engineering Science at the University of Auckland in 2008. In 2016, he completed a PhD at the Auckland Bioengineering Institute on Constitutive parameter identifiability and the design of experiments for applications in breast biomechanics under the supervision of Prof. Poul Nielsen and Prof. Martyn Nash. He is currently a postdoctoral research fellow at ABI, and a principal investigator in the Biomechanics for Breast Imaging research group.

Research | Current

Biomechanics for breast cancer imaging

Addressing clinical challenges involved in diagnosing and treating breast cancer by melding biomechanics, state-of-the-art image processing techniques, and population based statistical analysis. My work has led to the development of a clinical workflow that automatically builds personalised biomechanical models of the breast from diagnostic medical images, and predicts breast tissue motion during breast cancer diagnosis and treatment procedures. We are now trailing this workflow at Auckland City Hospital. Learn more about this research at the ABI's Biomechanics for Breast Imaging group project page.

Cardiac mechanics

Developing automated computational modelling worflows for predicting patient-specific cardiac mechanics to identify novel biomarkers for early detection of diseases such as heart failure. Learn more about this research on the ABI Cardiac mechanics project page.

Understanding the passive and active behaviour of cardiac muscles using computational models paired with rich experimental data from ABI's novel cardiac instrumentation devices.

Parameter estimation, design of experiments, and uncertainty quantification

Creating and validating frameworks for identifying the mechanical properties of soft tissues using noninvasive methods. The models are complemented with novel instrumentation and imaging techniques that we are currently developing in the ABI Bioinstrumentation Laboratory to create rich experimental datasets that can maximise identifiability of the mechanical properties.

Lung modelling

Developing novel real-time full-field stereoscopic imaging systems for tracking lung surface deformation during ventilation. The rich experimental data obatined from these imaging systems provides the information required for quantifying the stress-strain behaviour of alveoli during early maturity and senescence. 

Developing multi-scale computational models of the lung that use this novel experimental data to better understand the mechanisms behind decline in lung function with aging. These models will help guide the development of new diagnostic methods to distinguish age related changes from lung disease.

Learn more about this research at the ABI's Lungs and Respiratory System project page.

 

Project links

Teaching | Current

BIOMENG 321 - Continuum Modelling in Bioengineering

Areas of expertise

  • construction of patient-specific biomechanical models

  • computational mechanics

  • finite element analysis

  • soft tissue modelling

  • statistical shape analysis

  • stereovision

  • medical image processing & registration

  • soft-tissue constitutive parameter estimation

  • design of experiments techniques

  • high performance computing software development

Selected publications and creative works (Research Outputs)

Identifiers

Contact details

Primary office location

AUCKLAND BIOENGINEERING HOUSE - Bldg 439
Level 7, Room 719
70 SYMONDS ST
GRAFTON
AUCKLAND 1010
New Zealand

Web links