Ms Rojan Saghian

BSc MSc Shahid Beheshti University G.C.

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Doctoral Candidate - Doctor of Philosophy

Biography

Rojan attained a Bachelor of Science in Atomic Physics and a Master of Science in Elementary Particle and Quantum Field Theory Physics at the Shahid Beheshti University G.C. of Iran. She began her doctoral study at the Auckland Bioengineering Institute in 2013.
 

Research | Current

Thesis

Modelling the uterine circulation to understand the causes and consequences of inadequate spiral artery re-modelling

Rojan's research involves modelling the uterine circulation to understand the causes and consequences of inadequate spiral artery re-modelling. The aim of this work is to establish a computational model of the maternal spiral arteries that is able to relate in vitro measurements of cell migration to in vivo development.

This model will provide an initial framework that will:

  1. allow better design of cell migration experiments by indicating physiological shear stress and in the longer term chemo attractant signaling, and
  2. provide insight into the mechanisms that contribute to spiral artery remodeling in human pregnancy.

Supervisors


Research group

Lungs and Respiratory System

Selected publications and creative works (Research Outputs)

  • Saghian, R., James, J. L., Tawhai, M. H., Collins, S. L., & Clark, A. R. (2017). Association of Placental Jets and Mega-Jets With Reduced Villous Density. Journal of biomechanical engineering, 139 (5).10.1115/1.4036145
    Other University of Auckland co-authors: Jo James, Merryn Tawhai, Alys Clark
  • Saghian, R., James, J., Collins, S. L., Tawhai, M., & Clark, A. R. (2015). Modelling the relationship between maternal blood flow and villus tree density in normal human pregnancy. Placenta. 10.1016/j.placenta.2015.07.224
    Other University of Auckland co-authors: Jo James, Merryn Tawhai, Alys Clark
  • Clark, A. R., Lin, M., Tawhai, M., Saghian, R., & James, J. L. (2015). Multiscale modelling of the feto-placental vasculature. Interface focus, 5 (2).10.1098/rsfs.2014.0078
    URL: http://hdl.handle.net/2292/27890
    Other University of Auckland co-authors: Jo James, Merryn Tawhai, Alys Clark, Mabelle Yuling Lin
  • James, J. L., Saghian, R., Lin, M., Tawhai, M., & Clark, A. R. (25/3/2015). What can computational modelling teach us about the dynamic uteroplacental circulation in early human pregnancy?. Poster presented at Meeting of the Society for Reproductive Investigation, San Francisco, USA. Reproductive Sciences. Related URL.
    Other University of Auckland co-authors: Jo James, Merryn Tawhai, Alys Clark

Contact details

Primary location

UNISERVICES HOUSE - Bldg 439
Level 7 , Room 735
70 SYMONDS ST
AUCKLAND 1010
New Zealand