Dr Vicky Wang

BE(Hons) PhD

Research Fellow

Biography

Vicky Wang graduated from the University of Auckland with a Bachelor of Engineering (specialising in Biomedical Engineering) in 2006, and commenced working towards a doctorate at the Auckland Bioengineering Institute in 2007 under the supervision of Professors Martyn Nash and Alistair Young.

Her doctoral thesis focused on constructing a mathematical model of the heart - especially the left ventricle (LV) - from information obtained from two cardiac magnetic resonance imaging (MRI) techniques: tagged MRI and diffusion tensor MRI. This biophysical model can be used to simulate ventricular mechanics and consequently estimate myocardial mechanical properties.

Models between healthy and diseased cases (i.e. heart failure or diabetes) will allow more insights into the underlying mechanisms of these diseases. This framework can also provide information on regional distribution of stress and strain as well as local energy consumption. Works related to this project have been published in LNCS MICCAI 2008 and Medical Image Analysis.

On completion of her PhD, Vicky became a Research Fellow.

Research | Current

Vicky Wang's post-doctoral research focuses primarily on developing integrated physiological models of the heart that can provide insight into cardiac mechanics on an individualised basis. This type of research aims to improve our understanding of the underlying basis for mechanisms that affect cardiac muscle stiffness, and to help with clinical diagnosis for patients with heart failure.

Research groups

Teaching | Current

BIOMENG 321 Continuum Mechanics

Selected publications and creative works (Research Outputs)

Wang, Z. J., Wang, V. Y., Bradley, C. P., Nash, M. P., Young, A. A., & Cao, J. J. (2018). Left Ventricular Diastolic Myocardial Stiffness and End-Diastolic Myofibre Stress in Human Heart Failure Using Personalised Biomechanical Analysis. Journal of cardiovascular translational research, 11 (4), 346-356. 10.1007/s12265-018-9816-y
Other University of Auckland co-authors: Christopher Bradley, Martyn Nash, Alistair Young
Wang, V. Y., Hussan, J. R., Yousefi, H., Bradley, C. P., Hunter, P. J., & Nash, M. P. (2017). Modelling cardiac tissue growth and remodelling. Journal of Elasticity, 129 (1-2), 283-305. 10.1007/s10659-017-9640-7
URL: http://hdl.handle.net/2292/42638
Other University of Auckland co-authors: Jagir Hussan, Christopher Bradley, Peter Hunter, Martyn Nash
Wilson, A. J., Wang, V. Y., Sands, G. B., Young, A. A., Nash, M. P., & LeGrice, I. J. (2017). Increased cardiac work provides a link between systemic hypertension and heart failure. Physiological Reports, 5 (1)10.14814/phy2.13104
URL: http://hdl.handle.net/2292/35214
Other University of Auckland co-authors: Gregory Sands, Alistair Young, Martyn Nash, Ian LeGrice
Hasaballa, A. I., Sands, G. B., Wilson, A. J., Young, A. A., Wang, V. Y., LeGrice, I. J., & Nash, M. P. (2017). Three-dimensional quantification of myocardial collagen morphology from confocal images. In M. Pop, G. Wright (Eds.) Functional Imaging and Modelling of the Heart: 9th International Conference, FIMH 2017, Toronto, ON, Canada, June 11-13, 2017, Proceedings, 10263, 3-12. Cham: Springer International Publishing AG. 10.1007/978-3-319-59448-4_1
URL: http://hdl.handle.net/2292/35947
Other University of Auckland co-authors: Gregory Sands, Alistair Young, Ian LeGrice, Martyn Nash
Wang, V. Y., Casta, C., Zhu, Y. M., Cowan, B. R., Croisille, P., Young, A. A., ... Nash, M. P. (2016). Image-based investigation of human in vivo myofibre strain. IEEE Transactions on Medical Imaging, 35 (11), 2486-2496. 10.1109/TMI.2016.2580573
URL: http://hdl.handle.net/2292/32316
Other University of Auckland co-authors: Alistair Young, Martyn Nash
Chabiniok, R., Wang, V. Y., Hadjicharalambous, M., Asner, L., Lee, J., Sermesant, M., ... Nash, M. P. (2016). Multiphysics and multiscale modelling, data-model fusion and integration of organ physiology in the clinic: Ventricular cardiac mechanics. Interface Focus, 6 (2).10.1098/rsfs.2015.0083
URL: http://hdl.handle.net/2292/32321
Other University of Auckland co-authors: Alistair Young, Martyn Nash
Wang, V. Y., Niestrawska, J. A., Wilson, A. J., Sands, G. B., Young, A. A., LeGrice, I. J., & Nash, M. P. (2016). Image-driven constitutive modeling of myocardial fibrosis. International Journal for Computational Methods in Engineering Science and Mechanics, 17 (3), 211-221. 10.1080/15502287.2015.1082675
URL: http://hdl.handle.net/2292/30558
Other University of Auckland co-authors: Ian LeGrice, Alistair Young, Martyn Nash, Gregory Sands
Wang, Z., Wang, V. Y., Bradley, C. P., Nash, M. P., Young, A., & Cao, J. J. (2016). Quantifying passive myocardial stiffness and wall stress in heart failure patients using personalized ventricular mechanics. Journal of Cardiovascular Magnetic Resonance. 10.1186/1532-429X-18-S1-O17
URL: http://hdl.handle.net/2292/32326
Other University of Auckland co-authors: Christopher Bradley, Martyn Nash, Alistair Young