Auckland Bioengineering Institute
Biomechanics for Breast Imaging
New Zealand women have a 10% lifetime risk of developing breast cancer. Women self-identified as Máori have a twofold higher risk of developing breast cancer than non-Máori. Early detection by mammography (x-ray imaging of the compressed breast) currently offers the best chance of survival. However, small tumours are often difficult to identify because of poor contrast and lack of reliability in accounting for large deformations of breast tissue during compression. Current image registration algorithms account for tissue movement using heuristic approaches that are not based upon the physical principles that govern such deformations. The goal of this project is to develop a computational framework, based upon a quantitative model of the human breast, to facilitate the reliable interpretation of mammograms and other imaging modalities, such as MRI and ultrasound.
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We have developed computational techniques to track breast tissue motion under gravity. This can simulate, for example, a patient being reoriented from the prone position in an MR scanner to the supine position, for a subsequent biopsy or ultrasound procedure.
Techniques have been implemented that simulate compression during mammographic imaging. We have developed methods that collate microcalcifications between different mammographic views and track lesions across different modalities, such as x-ray mammography, MRI and ultrasound.
We are developing statistical models to analyse the spread of breast cancer through the lymphatic system. These models will enable clinicians to predict where a patient's primary tumour may spread, and has the potential to improve disease management.
Software applications are being developed to use our techniques in an intuitive and clinically-friendly way, with an emphasis on ensuring the software can be easily incorporated into the radiologist’s workflow. These applications will provide a visual framework for efficient breast care treatment.
The Biomechanics for Breast Imaging Group has filled all vacancies for its current research projects and research opportunities. Please check back for future opportunities with this research group.
The Biomechanics for Breast Imaging Project gratefully acknowledges the support of its funding partners:
- Foundation for Research Science and Technology
- The University of Auckland Research Fund
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